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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
27.58
Human Site:
Y173
Identified Species:
50.56
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
Y173
E
R
T
C
E
L
I
Y
L
T
Q
P
S
S
S
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
Y320
E
R
T
C
E
L
I
Y
L
T
Q
P
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
Y173
E
R
T
C
E
L
I
Y
L
T
Q
P
S
S
S
Dog
Lupus familis
XP_534118
897
103170
S151
T
Q
P
S
S
L
I
S
T
E
I
N
S
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
Y167
E
R
T
C
E
L
I
Y
L
T
Q
P
S
S
A
Rat
Rattus norvegicus
P33568
920
105007
Y166
E
R
T
C
G
L
I
Y
L
T
Q
P
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
Y158
E
R
I
C
G
L
I
Y
M
A
Q
P
S
S
Q
Chicken
Gallus gallus
Q90600
921
104417
Y161
E
R
T
C
G
L
I
Y
L
E
Q
P
S
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
T160
L
Y
Q
R
F
V
K
T
C
E
K
I
F
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
S156
D
I
S
R
P
P
R
S
R
R
H
K
A
M
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
E41
S
D
R
V
E
F
R
E
N
E
S
T
W
A
V
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
I200
S
S
D
K
Q
P
A
I
S
N
E
A
T
H
V
Maize
Zea mays
Q3LXA7
1010
111475
E184
K
S
S
D
N
S
S
E
S
N
N
Q
E
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
20
N.A.
93.3
86.6
N.A.
66.6
80
N.A.
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
86.6
N.A.
73.3
80
N.A.
20
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
8
8
24
8
% A
% Cys:
0
0
0
54
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
54
0
0
0
39
0
0
16
0
31
8
0
8
0
16
% E
% Phe:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
24
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
8
8
0
0
0
62
8
0
0
8
8
0
0
0
% I
% Lys:
8
0
0
8
0
0
8
0
0
0
8
8
0
0
0
% K
% Leu:
8
0
0
0
0
62
0
0
47
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
16
8
8
0
0
0
% N
% Pro:
0
0
8
0
8
16
0
0
0
0
0
54
0
0
8
% P
% Gln:
0
8
8
0
8
0
0
0
0
0
54
8
0
0
8
% Q
% Arg:
0
54
8
16
0
0
16
0
8
8
0
0
0
0
0
% R
% Ser:
16
16
16
8
8
8
8
16
16
0
8
0
62
54
31
% S
% Thr:
8
0
47
0
0
0
0
8
8
39
0
8
8
0
0
% T
% Val:
0
0
0
8
0
8
0
0
0
0
0
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
8
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _